This collection consists of information on events of the latter half of the twentieth century, most especially the assassination of John F. Kennedy. As the medical examiner who conducted the autopsies of Lee Harvey Oswald and Jack Ruby, Rose has a unique perspective on these events. One third of the collection consists of media coverage of the events, consisting of magazines, newspapers, and video cassettes. The remainder are personal papers of Mr. Rose, and here there are published articles (by other people than Rose, though he was interviewed for the Journal of the American Medical Society). He has gathered information on figures in the assassination and also those of other people, such as Sheriff Bill Decker. He apparently served as an advisor to the House Select Committee on Assassinations, and here are brought together materials to be submitted with that report. Rose has also written his recollections of events in Dallas, called Dallas: My View of History, for which there are manuscripts in this collection. Rose's correspondence and other miscellany round out the material.

There are materials of a sensitive nature in this collection that do not reflect the views of this institution.