The Marion Jones Clark papers date from 1930 to 2003 and measure 10 linear inches. The papers are arranged in two series: Personal and Professional.

The Personal series (1930-2003 and undated) contains primarily correspondence, educational records (including diplomas, certificates and transcripts from high school to graduate school), and financial records. During World War II, Marion Jones kept precise annual financial records and accumulated years of income tax forms to keep track of expenditures, both of which are reflected in her papers. Her war ration books along with her mileage ration records are included here. The correspondence includes thank-you cards and annual Christmas letters sent by Clark to family and friends summarizing the events of the year. The newspaper clipping included in this series describes Clark and her husband's work as volunteers with the music program at a local middle school. Photographs of Clark and her family, including her husband Arnold Clark, her three stepsons, Arnold Clark's parents, her sister-in-law, and her baby grandchild, complete the series.

The Professional series (1940-1960 and undated) concerns Marion Jones' career in the Department of Bacteriology at the State University of Iowa. This series contains departmental administrative reports and a bulletin with a photograph of Marion Jones. Also included are job offers, letters of appointment from the department, and her laboratory manuals and reports.