The Mary Berg papers date from 1911 to 2004 and measure 4.75 linear feet. The papers are arranged in eight series: Biographical, Anna Berg, Publications, Presentations, Professional Development, Research Files, Photographs, and Artifacts.

The Biographical series (1950-2004) includes information on Berg's childhood, hobbies, and friends, including National Philharmonic Director Stan Engebretson. Also included is Berg's personal correspondence and materials related to Berg's induction into the Iowa Women's Hall of Fame. Berg's CVs, professional biographies, and newspaper clippings that feature Berg's work are also part of this series.

The Anna Berg series (1911-2001) consists of materials related to Mary Berg's mother Anna Margaret Skramstad Berg, a native of North Dakota. A significant portion of the series contains information on the Skramstad family including several brief memoirs on the family's history. Two scrapbooks contain memorabilia from Anna Skramstad Berg's school years and newspaper clippings about North Dakota and the Skramstad family. Other materials include photocopied photographs and Anna Berg's mother's nursing diploma, dated 1911. The series also includes several books, some of which are written in Norwegian, and Anna Berg's travel journals from the family's trips to Europe. Correspondence in the series mostly consists of weekly letters from Anna Berg to her daughter, Mary Berg. In addition, the series includes substantial information about Anna Berg's illness and death.

The Publications series (1982-2001) is comprised of Berg's published work and conference papers on gender-related health issues. The four books Berg co-edited complete the series.

The Presentations series (1987-2001) includes materials used in, or related to, Berg's presentations at pharmaceutical and women's health conferences around the world. These materials are organized chronologically and include abstracts, lecture notes, presentation slides, as well as brochures and booklets from the conferences.

The Professional Development series (1985-2004) includes materials on conferences Berg helped organize as well as several committees on which she served. It also includes scholarly papers written by Neil Cummings, a colleague of Berg's, which Mary Berg edited. This series contains information on Berg's activities at the University of Iowa including her efforts to become the first women full professor in the College of Pharmacy.

The Research Files series (1987-2002) includes publications and newspaper articles related to Berg's research. It also includes newspaper articles related to gender inequity in academia and the field of pharmacy.

The Photographs series (1911-2002) is comprised of family and professional photographs. Included are Anna Skramstad Berg's photograph albums from her childhood and teenage years. The Artifacts series (1974-1978) includes two mortar and pestles given to Berg upon receipt of her MA and PhD, and a small fabric banner from Berg's lecture series at China Pharmaceutical University.